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Poly(methacrylic acid)‐Grafted Carbon Nanotube Scaffolds Enhance Differentiation of hESCs into Neuronal Cells
Author(s) -
Chao TzuI,
Xiang Shuhuai,
Lipstate Jessica Faye,
Wang Changchun,
Lu Jennifer
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201000262
Subject(s) - materials science , carbon nanotube , methacrylic acid , nanotechnology , regeneration (biology) , cellular differentiation , microbiology and biotechnology , polymerization , polymer , biochemistry , biology , composite material , gene
Poly(methacrylic acid)‐grafted carbon nanotube‐based thin films are found to significantly improve the neuronal differentiation efficiency, and relatively mature neuronal cells have been derived directly from hESCs, owing to their excellent protein sequestration ability and nanofibrillar characteristics. This novel material platform creates new opportunities in the tissue regeneration field.