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Development of Extracellular Matrices Mimicking Stepwise Adipogenesis of Mesenchymal Stem Cells
Author(s) -
Hoshiba Takashi,
Kawazoe Naoki,
Tateishi Tetsuya,
Chen Guoping
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201000038
Subject(s) - adipogenesis , mesenchymal stem cell , stem cell , biology , microbiology and biotechnology , extracellular matrix , computational biology , materials science , computer science
A novel type of extracellular matrices , stepwise adipogenesis‐mimicking matrices, was developed from cultured mesenchymal stem cells controlled at different stages of adipogenesis. The matrices derived from stem cells, and the cells controlled at early and late stages of adipogenesis showed different effects on stem cell differentiation.