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Microfluidics: Surface‐Treatment‐Induced Three‐Dimensional Capillary Morphogenesis in a Microfluidic Platform (Adv. Mater. 47/2009)
Author(s) -
Chung Seok,
Sudo Ryo,
Zervantonakis Ioannis K.,
Rimchala Tharathorn,
Kamm Roger D.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200990175
Subject(s) - microfluidics , materials science , capillary action , nanotechnology , matrix (chemical analysis) , biomedical engineering , confocal , angiogenesis , composite material , optics , biology , medicine , physics , cancer research
The cover shows confocal images of 3D sprouting into matrix material in microfluidic channels. Roger Kamm and co‐workers report on p. 4863 that robust induction of realistic angiogenesis into the 3D matrix material under simultaneous imaging and a stably controlled concentration gradient of chemoattractants can be achieved. The formation of a 3D vascular network is demonstrated to be a direct consequence of surface treatment of the region of the device‐containing matrix material.