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Mercury Biosensors: Polydiacetylene–Liposome Microarrays for Selective and Sensitive Mercury(II) Detection (Adv. Mater. 36/2009)
Author(s) -
Lee Jiseok,
Jun Hayeon,
Kim Jinsang
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200990140
Subject(s) - mercury (programming language) , biosensor , liposome , materials science , aptamer , nanotechnology , fluorescence , dna microarray , epoxy , chemistry , microbiology and biotechnology , composite material , optics , biology , biochemistry , gene expression , physics , computer science , gene , programming language
Polydiacetylene (PDA) liposome microarrays have been developed for selective and sensitive mercury detection. The sensors, reported on p. 3674 by Jinsang Kim and co‐workers, are designed to produce red fluorescence emission upon binding with Hg 2+ ; when the single‐stranded DNA aptamers on the microarray selectively wrap around the mercury ions, the resulting complexes repulse each other. The epoxy‐based PDA liposome design is an excellent universal platform that can be readily extended to other sensor designs.