Premium
DNA Sensors: Highly Sensitive, Mechanically Stable Nanopore Sensors for DNA Analysis (Adv. Mater. 27/2009)
Author(s) -
Venkatesan Bala Murali,
Dorvel Brian,
Yemenicioglu Sukru,
Watkins Nicholas,
Petrov Ivan,
Bashir Rashid
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200990100
Subject(s) - nanopore , materials science , nanotechnology , dna , biosensor , nanopore sequencing , dna sequencing , chemistry , biochemistry
A new solid state nanopore biosensor for the analysis of individual DNA molecules is reported by Rashid Bashir and co‐workers on p. 2771 . The cover illustrates the passage of double‐stranded DNA through an Al 2 O 3 nanopore sensor fabricated using ALD and e‐beam‐induced sputtering processes. Hexagonal γ‐phase Al 2 O 3 nanocrystallites form during pore formation as shown, improving the mechanical stability and sensitivity of these nanopore sensors. The CMOS‐compatible nature of this process establishes this technology as a potential candidate for next‐generation DNA sequencing.