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Chemical Nanosensors Based on Composite Molecularly Imprinted Polymer Particles and Surface‐Enhanced Raman Scattering
Author(s) -
Bompart Marc,
De Wilde Yannick,
Haupt Karsten
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200904442
Subject(s) - nanosensor , molecularly imprinted polymer , materials science , nanotechnology , nanoparticle , polymer , composite number , analyte , raman scattering , raman spectroscopy , composite material , optics , organic chemistry , chemistry , selectivity , chromatography , physics , catalysis
Chemical nanosensors with a submicrometer core–shell composite design , based on a polymer core, a molecularly imprinted polymer (MIP) shell for specific analyte recognition, and an interlayer of gold nanoparticles for signal amplification, are described. SERS measurements on single nanosensors yield detection limits of 10 −7 M for the β ‐blocker propranolol, several orders of magnitude lower than on plain MIP spheres.