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High‐Strength Hydrogels with Integrated Functions of H‐bonding and Thermoresponsive Surface‐Mediated Reverse Transfection and Cell Detachment
Author(s) -
Tang Lei,
Liu Wenguang,
Liu Guipei
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200904016
Subject(s) - self healing hydrogels , materials science , monomer , copolymer , transfection , regeneration (biology) , polymer , chemical engineering , lower critical solution temperature , nanotechnology , polymer chemistry , composite material , microbiology and biotechnology , chemistry , gene , biochemistry , biology , engineering
The construction of a high‐strength hydrogel with integrated functions by photo‐initiated copolymerization of temperature‐sensitive and hydrogen‐bonding monomers is described. The hydrogen‐bonding and thermoresponsive surface of hydrogels offers a multifunctional platform, where reverse gene transfection and gene‐modified cell detachment can be achieved for the potential use in the regeneration and replacement of soft tissue.