Premium
Two‐Photon Excited Fluorescence Enhancement for Ultrasensitive DNA Detection on Large‐Area Gold Nanopatterns
Author(s) -
Jung JinMi,
Yoo HaeWook,
Stellacci Francesco,
Jung HeeTae
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200903745
Subject(s) - fluorescence , excited state , materials science , nanotechnology , photon , molecule , sensitivity (control systems) , two photon excitation microscopy , optoelectronics , optics , physics , atomic physics , electronic engineering , engineering , quantum mechanics
Ultrasensitive DNA detection using enhanced two‐photon excited fluorescence: DNA detection systems formed on a highly regular gold nanopattern over a large area show enhanced sensitivity from high to ultralow concentrations (∼10−11 M , see figure) target molecules. The observed two‐photon excited fluorescence on the gold patterned surface is enhanced over two orders of magnitude compared with the molecules on the glass surface.