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Assemblies of Conjugated Polyelectrolytes with Proteins for Controlled Protein Photoinactivation
Author(s) -
Duan Xinrui,
Liu Libing,
Feng Xuli,
Wang Shu
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200903716
Subject(s) - conjugated system , polyelectrolyte , materials science , polymer , irradiation , metal , biophysics , nanotechnology , biology , composite material , physics , nuclear physics , metallurgy
Conjugated polyelectrolytes are used to specifically inactivate proteins under light irradiation through their assemblies with proteins by electrostatic or metal ion‐mediated coordination interactions. Upon light irradiation, the polymer produces reactive oxygen species that react with and inactivate adjacent proteins. The present work adds a new dimension to the function of conjugated polymers.