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Particle/Fluid Interface Replication as a Means of Producing Topographically Patterned Polydimethylsiloxane Surfaces for Deposition of Lipid Bilayers
Author(s) -
Subramaniam Anand Bala,
Lecuyer Sigolene,
Ramamurthi Kumaran S.,
Losick Richard,
Stone Howard A.
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200903625
Subject(s) - aerospace , engineering physics , library science , engineering , aerospace engineering , computer science
A simple method to produce topographically patterned substrates from polydimethylsiloxane (PDMS) is presented. Surfaces with positively or negatively curved features, a combination of positively and negatively curved features or geometrically complex biomimetic features are fabricated. High‐quality lipid bilayers that conform to the topography of the substrates can be prepared, a characteristic useful for biophysical studies.