Premium
Hydrophilic Co@Au Yolk/Shell Nanospheres: Synthesis, Assembly, and Application to Gene Delivery
Author(s) -
Lu Yang,
Zhao Yang,
Yu Le,
Dong Liang,
Shi Ce,
Hu MingJun,
Xu YunJun,
Wen LongPing,
Yu ShuHong
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200903298
Subject(s) - nanocages , materials science , nanotechnology , superparamagnetism , gene delivery , biocompatible material , etching (microfabrication) , nanoparticle , transfection , biomedical engineering , gene , magnetization , chemistry , organic chemistry , catalysis , medicine , biochemistry , physics , layer (electronics) , quantum mechanics , magnetic field
Co@Au yolk/shell nanospheres and linear assemblies of such are synthesized by controlled galvanic replacement reaction. The nanospheres are biocompatible, hydrophilic, and superparamagnetic, and gold nanocages can be prepared by etching. The potential applications of the nanospheres include use as nonviral gene transport vehicles, cellular optical imaging, and in vivo magnetic resonance imaging tracking during gene transfection.