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Conjugated Polyelectrolyte–Metal Nanoparticle Platforms for Optically Amplified DNA Detection
Author(s) -
Wang Yusong,
Liu Bin,
Mikhailovsky Alexander,
Bazan Guillermo C.
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200902675
Subject(s) - nanoparticle , materials science , polyelectrolyte , fluorescence , nanotechnology , conjugated system , silver nanoparticle , metal , optics , polymer , physics , composite material , metallurgy
A conjugated polyelectrolyte (CPE)‐silver nanoparticle platform for DNA‐sensing applications is fabricated (see figure), which provides over 17‐fold enhancement of dye emission intensity, as compared to the intrinsic dye emission observed atop a conventional glass surface. Examination of the distance‐dependence amplification process reveals that the role of the silver nanoparticles is to increase the effective field experienced by the light‐harvesting CPE, and the metal enhanced fluorescence of the CPE could be translated into higher dye signal intensities for the detection platform.