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Controlling the Number of Proteins with Dip‐Pen Nanolithography
Author(s) -
Bellido Elena,
de Miguel Rocío,
RuizMolina Daniel,
Lostao Anabel,
Maspoch Daniel
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200902372
Subject(s) - nanolithography , dip pen nanolithography , ferritin , nanotechnology , materials science , particle (ecology) , chemistry , fabrication , medicine , biochemistry , alternative medicine , pathology , oceanography , geology
Desired numbers of proteins can be positioned on surfaces by using dip‐pen nanolithography (DPN). Ferritin nanoarrays are fabricated by direct‐writing nanodroplets of a ferritin solution on TEM surfaces. After the contact‐angle value of these droplets is determined, the concentration of the inking protein solution and the diameter of the dot‐like feature can be modulated to position a single ferritin particle on a surface (see figure).

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