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A Polymersome Nanoreactor with Controllable Permeability Induced by Stimuli‐Responsive Block Copolymers
Author(s) -
Kim Kyoung Taek,
Cornelissen Jeroen J. L. M.,
Nolte Roeland J. M.,
van Hest Jan C. M.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200900300
Subject(s) - polymersome , nanoreactor , copolymer , amphiphile , boronic acid , materials science , membrane , covalent bond , phenylboronic acid , polymer chemistry , chemical engineering , nanotechnology , combinatorial chemistry , organic chemistry , chemistry , polymer , nanoparticle , biochemistry , catalysis , composite material , engineering
A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli‐responsive boronic acid‐containing block copolymers is reported. The latter block copolymers form phase‐separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.