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Antimicrobial Activity of Silver Nanocrystals Encapsulated in Mesoporous Silica Nanoparticles
Author(s) -
Liong Monty,
France Bryan,
Bradley Kenneth A.,
Zink Jeffrey I.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200802646
Subject(s) - mesoporous silica , nanocrystal , materials science , antimicrobial , nanotechnology , nanoparticle , dissolution , silver nanoparticle , amphiphile , mesoporous material , coating , chemical engineering , organic chemistry , copolymer , chemistry , polymer , catalysis , engineering , composite material
Silver nanocrystals encapsulated in mesoporous silica nanoparticles are prepared by coating hydrophobic silver nanocrystals with amphiphilic surfactants and growing mesostructured silica around the materials. The nanoparticles can be used as antimicrobial agents for both Gram‐positive and ‐negative bacteria through oxidative dissolution of the silver nanocrystals. The surface characteristics of the silica exterior affect the binding to the bacteria and the cytotoxicity.