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Encoded Porous Beads for Label‐Free Multiplex Detection of Tumor Markers
Author(s) -
Zhao Yuanjin,
Zhao Xiangwei,
Hu Jing,
Xu Ming,
Zhao Wenju,
Sun Liguo,
Zhu Cun,
Xu Hua,
Gu Zhongze
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200802339
Subject(s) - materials science , multiplex , nanotechnology , porosity , composite material , biology , genetics
Inverse‐opaline photonic beads are used as the elements of a suspension array for label‐free multiplex immunoassays. As in the case of tumor‐marker detection, specific binding of tumor markers on the pore surfaces of the beads results in a shift in the diffraction‐peak position, which can be used for quantitatively estimating the amount of bound tumor marker.