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Defocused Wide‐field Imaging Unravels Structural and Temporal Heterogeneity in Complex Systems
Author(s) -
Dedecker Peter,
Muls Benoît,
Deres Ania,
Ujii Hiroshi,
Hotta Junichi,
Sliwa Michel,
Soumillion JeanPhilippe,
Müllen Klaus,
Enderlein Jörg,
Hofkens Johan
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200801873
Subject(s) - structuring , nanotechnology , materials science , field (mathematics) , nanoscopic scale , complex system , computer science , artificial intelligence , mathematics , finance , pure mathematics , economics
Today's miniature devices and biological systems share the fact that their dynamics and properties cannot be understood in terms of macroscopic concepts, but require a thorough understanding of the nanoscale structuring. This structuring is often very heterogeneous, both in time and in space, and is difficult or impossible to resolve with traditional approaches. In this Progress Report, we will discuss how single‐molecule microscopy—and defocused wide‐field imaging in particular—can be used to shed light on these phenomena.