Mineral‐Coated Polymer Microspheres for Controlled Protein Binding and Release | Zendy

Jongpaiboonkit Leenaporn | Zendy; FranklinFord Travelle | Zendy; Murphy William L. | Zendy

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Mineral‐Coated Polymer Microspheres for Controlled Protein Binding and Release

Author(s) -

Jongpaiboonkit Leenaporn,

FranklinFord Travelle,

Murphy William L.

Publication year - 2009

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.200801808

Subject(s) - microsphere , polymer , materials science , coating , molecule , nanotechnology , controlled release , combinatorial chemistry , chemical engineering , organic chemistry , chemistry , engineering , composite material

Polymer microspheres with a bone‐like mineral coatings are generated via a biomimetic process, and this biodegradable coating is used as a carrier for delivery of biological molecules. Acidic and basic proteins are controllably bound and released from these microspheres, suggesting that this approach can be used for binding and delivery of a broad range of biologically active molecules.

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