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Mineral‐Coated Polymer Microspheres for Controlled Protein Binding and Release
Author(s) -
Jongpaiboonkit Leenaporn,
FranklinFord Travelle,
Murphy William L.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200801808
Subject(s) - microsphere , polymer , materials science , coating , molecule , nanotechnology , controlled release , combinatorial chemistry , chemical engineering , organic chemistry , chemistry , engineering , composite material
Polymer microspheres with a bone‐like mineral coatings are generated via a biomimetic process, and this biodegradable coating is used as a carrier for delivery of biological molecules. Acidic and basic proteins are controllably bound and released from these microspheres, suggesting that this approach can be used for binding and delivery of a broad range of biologically active molecules.