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3D Cell‐Migration Studies using Two‐Photon Engineered Polymer Scaffolds
Author(s) -
Tayalia Prakriti,
Mendonca Cleber R.,
Baldacchini Tommaso,
Mooney David J.,
Mazur Eric
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200801319
Subject(s) - materials science , polymer , two photon excitation microscopy , tissue engineering , nanotechnology , composite material , biomedical engineering , fluorescence , optics , physics , medicine
We use two‐photon polymerization to fabricate 3D scaffolds with precise control over pore size and shape for studying cell migration in 3D. These scaffolds allow movement of cells in all directions. The fabrication, imaging, and quantitative analysis method developed here can be used to do systematic cell studies in 3D.