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The Effect of NaF In Vitro on the Mechanical and Material Properties of Trabecular and Cortical Bone
Author(s) -
Thurner Philipp J.,
Erickson Blake,
Turner Patricia,
Jungmann Ralf,
Lelujian Jason,
Proctor Alexander,
Weaver James C.,
Schitter Georg,
Morse Daniel E.,
Hansma Paul K.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200801204
Subject(s) - materials science , softening , indentation , trabecular bone , composite material , sodium fluoride , elastic modulus , cortical bone , modulus , fluoride , anatomy , chemistry , inorganic chemistry , osteoporosis , medicine
High doses of sodium fluoride in bones lead to severe softening , by weakening interfacial properties between the inorganic minerals and the organic components, while leaving mineralization unchanged. This leads to reduction of microdamage and associated stress‐whitening pointing to a change in failure mode. Accordingly, elastic modulus, failure stress, and indentation‐distance increase are decreased, whereas failure strain is increased.