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Aligned Cell Sheets Grown on Thermo‐Responsive Substrates with Microcontact Printed Protein Patterns
Author(s) -
Williams Corin,
Tsuda Yukiko,
Isenberg Brett C.,
Yamato Masayuki,
Shimizu Tatsuya,
Okano Teruo,
Wong Joyce Y.
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200801027
Subject(s) - microcontact printing , materials science , 3d printed , nanotechnology , biomedical engineering , medicine
The thermo‐responsive polymer poly( N ‐isopropylacrylamide) is microcontact printed with fibronectin lanes. Cells seeded onto these substrates form globally aligned tissue sheets that can be harvested by lowering the temperature.