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Surface‐Enhanced Raman Detection on Metalized Nanostructured Poly( p ‐xylylene) Films
Author(s) -
Kao Ping,
Malvadkar Niranjan A.,
Cetinkaya Murat,
Wang Hui,
Allara David L.,
Demirel Melik C.
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200800936
Subject(s) - materials science , xylylene , substrate (aquarium) , evaporation , nanotechnology , polymerization , polymer , raman spectroscopy , thin film , chemical engineering , optics , polymer chemistry , composite material , oceanography , physics , engineering , thermodynamics , geology
The development of a SERS substrate with high uniformity and sample‐to‐sample reproducibility is reported. Nanostructured poly( p ‐xylylene) films are prepared using an oblique‐angle polymerization method, and SERS‐active metals are deposited onto the nanostructured polymer by using thermal evaporation (see figure). The use of the substrate for a robust and reagentless detection of both Gram‐positive and Gram‐negative bacteria is demonstrated.