Premium
Injectable Superparamagnetic Ferrogels for Controlled Release of Hydrophobic Drugs
Author(s) -
Qin Jian,
Asempah Isaac,
Laurent Sophie,
Fornara Andrea,
Muller Robert N.,
Muhammed Mamoun
Publication year - 2009
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200800764
Subject(s) - materials science , superparamagnetism , poloxamer , drug delivery , chemical engineering , nanotechnology , composite material , polymer , copolymer , magnetization , physics , quantum mechanics , magnetic field , engineering
A ferrogel for magnetically controlled release of drugs is prepared by integration of superparamagnetic iron oxide nanoparticles and Pluronic F127 gels. The hydrophobic drug indomethacin is loaded in the ferrogel owing to the oil‐in‐water micellar structure. The characteristic sol–gel transition property renders the ferrogel an injectable drug carrier that will be, in principle, free from surgical implant procedure.