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Inside Front Cover: Hybrid Nanoparticles for Magnetic Resonance Imaging of Target‐Specific Viral Gene Delivery (Adv. Mater. 20/2007)
Author(s) -
Huh Y.M.,
Lee E.S.,
Lee J.H.,
Jun Y.w.,
Kim P.H.,
Yun C.O.,
Kim J.H.,
Suh J.S.,
Cheon J.
Publication year - 2007
Publication title -
advanced materials
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200790080
Subject(s) - materials science , gene delivery , nanoparticle , green fluorescent protein , magnetic resonance imaging , nanobiotechnology , in vivo , nanotechnology , gene , nuclear magnetic resonance , genetic enhancement , biology , medicine , biochemistry , physics , radiology , microbiology and biotechnology
The inside cover displays multifunctional “adenovirus‐magnet” nanoparticles possessing target‐specific infection, magnetic resonance imaging (MRI), and gene expression capabilities. These hybrid nanoparticles, reported by Jin‐Suck Suh, Jinwoo Cheon, and co‐workers on p. 3109 in the Special Section on Bionanotechnology, selectively target the Coxsackievirus B adenovirus receptor (CAR)‐positive cells and deliver the gene of enhanced green fluorescent protein (eGFP), while simultaneously being imaged by MRI. These hybrid nanoparticles can be regarded as new probes for in vivo MRI tracking of targeted viral gene delivery, which is essential for next‐generation diagnostics and therapeutics.