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Sensitivity Enhancement of Surface‐Plasmon Resonance Imaging by Nanoarrayed Organothiols
Author(s) -
Lisboa Patrícia,
Valsesia Andrea,
Mannelli Ilaria,
Mornet Stephane,
Colpo Pascal,
Rossi François
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200702736
Subject(s) - surface plasmon resonance , sensitivity (control systems) , biosensor , materials science , nanotechnology , biomolecule , surface plasmon , plasmon , resonance (particle physics) , surface (topology) , optoelectronics , nanoparticle , physics , electronic engineering , geometry , mathematics , particle physics , engineering
Crystalline organothiol nanoarrays improve the detection sensitivity of surface‐plasmon resonance (SPR) by a factor of five in comparison to noncrystalline nanopatterns and uniformly carboxylic surfaces. SPR images taken during the detection of an immunoreaction show a brighter color in the nanoarray area of the surface, which is the result of higher detection sensitivity. Sensor surfaces with nanoarrays may therefore provide future applications for the immobilization of biomolecules on biosensing surfaces.