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Surface Gradient of Functional Heparin
Author(s) -
Robinson David E.,
Marson Andrew,
Short Robert D.,
Buttle David J.,
Day Anthony J.,
Parry Kristina L.,
Wiles Michelle,
Highfield Peter,
Mistry Anita,
Whittle Jason D.
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200702586
Subject(s) - heparin , materials science , adsorption , polymerization , amine gas treating , surface (topology) , polymer , chemical engineering , polymer chemistry , composite material , organic chemistry , chemistry , biochemistry , geometry , mathematics , engineering
A gradient of functional heparin is fabricated onto a surface chemical gradient of plasma‐polymerized allyl amine (see figure). While heparin functionality changes across the gradient, increased adsorption of heparin onto the surface is not accompanied with a continued, corresponding rise in heparin function.