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Multiplex Imaging of Pancreatic Cancer Cells by Using Functionalized Quantum Rods
Author(s) -
Yong KenTye,
Roy Indrajit,
Pudavar Haridas E.,
Bergey Earl J.,
Tramposch Kenneth M.,
Swihart Mark T.,
Prasad Paras N.
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200702462
Subject(s) - pancreatic cancer , multiplex , materials science , quantum dot , monoclonal antibody , nanotechnology , mesothelin , cancer , cancer research , optoelectronics , bioinformatics , biology , antibody , genetics
A technique for labeling of live human cancer cells is presented. The imaging technique employs semiconductor quantum rods of CdSe/CdS/ZnS for multiplex labeling. The technique is further used to diagnose human pancreatic cancer by conjugating QRs with monoclonal antibodies (anti‐Claudin 4 and anti‐mesothelin).