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Electrically Programmable Surfaces for Configurable Patterning of Cells
Author(s) -
Fan Chao Yung,
Tung YiChung,
Takayama Shuichi,
Meyhöfer Edgar,
Kurabayashi Katsuo
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200702191
Subject(s) - materials science , c2c12 , extracellular matrix , electrode , microfluidics , nanotechnology , copolymer , surface modification , surface (topology) , morphology (biology) , myocyte , optoelectronics , composite material , polymer , chemical engineering , microbiology and biotechnology , myogenesis , chemistry , geometry , mathematics , genetics , engineering , biology
A microfluidic device surface coated with block copolymer and extracellular matrix (ECM) protein layers (see Figure) shows electrical programmability for cell immobilization. The surface has demonstrated the ability to pattern C2C12 murine myoblasts cells with their morphology and surface density adjustable by varying the applied electrode bias.