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Non‐Lithographic Wrinkle Nanochannels for Protein Preconcentration
Author(s) -
Chung Seok,
Lee Jeong Hoon,
Moon MyoungWoon,
Han Jongyoon,
Kamm Roger D.
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200701715
Subject(s) - materials science , wrinkle , nanotechnology , lithography , optoelectronics , composite material
A simple, non‐lithographic method to create a nanofluidic channel array that exploits wrinkles is demonstrated. The dimension and position of the wrinkles can be precisely controlled, producing wrinkle nanochannels (WNCs) that range in size from several tens of nanometers to micrometers. The usefulness of the WNCs is demonstrated by preconcentration of a protein, which is shown to vary linearly. Preconcentration levels of more than 100 can be achieved within 10 minutes.