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Cartilage Tissue Engineering in Plasma and Whole Blood Scaffolds
Author(s) -
Haberhauer Marcus,
Zernia Göran,
Deiwick Andrea,
Pösel Claudia,
Bader Augustinus,
Huster Daniel,
Schulz Ronny M.
Publication year - 2008
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200701344
Subject(s) - extracellular matrix , cartilage , tissue engineering , materials science , matrix (chemical analysis) , biomedical engineering , extracellular , plasma , biochemistry , chemistry , anatomy , composite material , biology , engineering , physics , quantum mechanics
Plasma and whole blood based scaffolds were used for cartilage tissue engineering . Chondrocytes were isolated, embedded into these structures, and cultivated for two weeks. To evaluate the neo‐synthesized extracellular matrix quantitatively, the constructs were examined by classical techniques and NMR spectroscopy. Significant expression of characteristic extracellular matrix was found suggesting that these materials are well‐suited grafts for artificial tissue.