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Cover Picture: A Micropatterned Hydrogel Platform for Chemical Synthesis and Biological Analysis (Adv. Mater. 5/2006)
Author(s) -
Zourob M.,
Gough J. E.,
Ulijn R. V.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200690022
Subject(s) - micropatterning , biochip , materials science , ethylene glycol , peptide , nanotechnology , peptide synthesis , self healing hydrogels , polymer chemistry , organic chemistry , chemistry , biochemistry
A polymer hydrogel platform for peptide arrays compatible with both solid‐phase peptide synthesis conditions and the aqueous environment essential for biological assays is reported on p. 655 by Ulijn and co‐workers. Micropatterning followed by multiple‐step peptide synthesis produces the peptide‐functionalized poly(ethylene glycol)–polyamide “biochips” shown schematically on the cover. On‐chip biological assays involving cells and enzymes provide proof‐of‐concept.