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Bioavailability of Nickel in Single‐Wall Carbon Nanotubes
Author(s) -
Liu X.,
Gurel V.,
Morris D.,
Murray D. W.,
Zhitkovich A.,
Kane A. B.,
Hurt R. H.
Publication year - 2007
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200602696
Subject(s) - carbon nanotube , nickel , bioavailability , materials science , intracellular , nanotechnology , heavy metals , catalysis , carbon fibers , chemical engineering , environmental chemistry , chemistry , organic chemistry , metallurgy , bioinformatics , biochemistry , biology , composite material , engineering , composite number
The biomolecular mechanism of nickel carcinogenicity is driven by intracellular Ni cation. The role of nickel catalyst in single‐wall carbon nanotube toxicity will therefore depend on its bioavailability, which is highly uncertain due to encapsulation by carbon shells. This article measures the material‐specific Ni release into extra‐ and intracellular physiological fluid phases and suggests practical techniques for managing the metals contribution to SWNT toxicity.