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A Cleavable‐Polycation Template Method for the Fabrication of Noncrosslinked, Porous Polyelectrolyte Multilayered Films
Author(s) -
Chen J.,
Xia X.M.,
Huang S.W.,
Zhuo R.X.
Publication year - 2007
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200601588
Subject(s) - polyelectrolyte , materials science , fabrication , layer by layer , nanotechnology , layer (electronics) , polymer , drug delivery , porosity , composite material , medicine , alternative medicine , pathology
Porous, noncrosslinked polyelectrolyte‐complex thin films (see figure), which will find applications in biomedicine, for example for drug or gene delivery, are achieved by using a simple, mild, and efficient method. Layer‐by‐layer assembly of polyanion and a blend of two polycations is followed by removal of the reductively degradable polycation template in the multilayered film in dithiothreitol solution.