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Direct Printing of Bioceramic Implants with Spatially Localized Angiogenic Factors
Author(s) -
Gbureck U.,
Hölzel T.,
Doillon C. J.,
Müller F. A.,
Barralet J. E.
Publication year - 2007
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200601370
Subject(s) - brushite , bioceramic , materials science , nanotechnology , biomedical engineering , bone grafting , metallurgy , dentistry , calcium , medicine
Direct printing of brushite and hydroxyapatite bioceramics at room temperature is used to construct model implants onto which the angiogenic compounds vascular endothelial growth factor (VEGF) and copper sulfate were adsorbed. This low‐temperature direct approach offers several practical advantages and may find application in bone grafting. The figure shows examples of complex shapes made of brushite.