Premium
Asymmetric Functionalization of Nanoparticles Based on Thermally Addressable DNA Interconnects
Author(s) -
Huo F.,
LyttonJean A. K. R.,
Mirkin C. A.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200601178
Subject(s) - valency , materials science , surface modification , nanoparticle , particle (ecology) , oligonucleotide , nanotechnology , chemical engineering , dna , chemistry , engineering , biology , biochemistry , philosophy , linguistics , ecology
The synthesis of nanoparticles asymmetrically functionalized with oligonucleotides is reported. The method provides excellent control over the placement of oligonucleotides on the surface of only one hemisphere of each particle (see figure). This new synthetic capability allows one to introduce valency into such structures and then use that valency to direct particle‐assembly events.