Premium
Biocompatible, Hydrophilic, Supramolecular Carbon Nanoparticles for Cell Delivery
Author(s) -
Yan A.,
Lau B. W.,
Weissman B. S.,
Külaots I.,
Yang N. Y. C.,
Kane A. B.,
Hurt R. H.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200600838
Subject(s) - materials science , nanoparticle , surface modification , nanotechnology , biocompatible material , carbon fibers , supramolecular chemistry , chemical engineering , aqueous solution , dispersion (optics) , liquid crystal , crystal structure , organic chemistry , composite material , biomedical engineering , chemistry , medicine , physics , optoelectronics , optics , composite number , engineering
Liquid‐crystal self‐assembly is used to fabricate carbon nanoparticles specially suited for cell‐delivery applications (see figure). The nanoparticles possess high‐activity surfaces for easy functionalization and aqueous dispersion, and are shown to be rapidly internalized by mesothelial cells, wherein they show no measurable toxicity relative to crystalline silica used as a positive control.