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In Vivo Magnetic Resonance Imaging of Single‐Walled Carbon Nanohorns by Labeling with Magnetite Nanoparticles
Author(s) -
Miyawaki J.,
Yudasaka M.,
Imai H.,
Yorimitsu H.,
Isobe H.,
Nakamura E.,
Iijima S.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200502174
Subject(s) - materials science , magnetite nanoparticles , magnetite , magnetic resonance imaging , nanoparticle , in vivo , nanotechnology , magnetic nanoparticles , nuclear magnetic resonance , carbon fibers , composite material , metallurgy , radiology , medicine , microbiology and biotechnology , biology , composite number , physics
Nanoparticles of superparamagnetic magnetite have been strongly attached to single‐walled carbon nanohorns (SWNHs) by using a simple method, namely the deposition of iron acetate clusters on SWNHs followed by heat treatment. The attached magnetite nanoparticles induce remarkable darkening of the magnetic resonance images, which allowed in vivo visualization (see figure) of the accumulative behavior of SWNHs in the spleen and kidneys.