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Nanoporous Protein Particles Through Templating Mesoporous Silica Spheres
Author(s) -
Wang Y.,
Caruso F.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200501901
Subject(s) - nanoporous , materials science , mesoporous material , nanotechnology , mesoporous silica , template , spheres , fabrication , particle (ecology) , copolymer , nanoparticle , polyelectrolyte , chemical engineering , organic chemistry , polymer , chemistry , composite material , catalysis , physics , astronomy , engineering , medicine , alternative medicine , oceanography , pathology , geology
Sequential assembly of protein and polyelectrolyte in mesoporous silica (MS) spheres leads to the formation of nanoporous protein particles (NPPs); the MS templates are removed after the fabrication process (see figure). The NPPs based on catalase show excellent biological activity, with up to 57 % of the activity retained. This strategy offers a novel and effective method of preparing bioactive NPPs of diverse composition, particle size, and shape.