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Rigid, Self‐Assembled Hydrogel Composed of a Modified Aromatic Dipeptide
Author(s) -
Mahler A.,
Reches M.,
Rechter M.,
Cohen S.,
Gazit E.
Publication year - 2006
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200501765
Subject(s) - materials science , biocompatible material , dipeptide , self healing hydrogels , biomaterial , rigidity (electromagnetism) , self assembly , nanotechnology , self healing , biocompatibility , tissue engineering , drug delivery , copolymer , biomedical engineering , polymer chemistry , composite material , polymer , peptide , chemistry , biochemistry , pathology , medicine , alternative medicine , metallurgy
A simple dipeptide self‐assembles into a biocompatible hydrogel (see figure and inside cover). This novel biomaterial is extremely simple to prepare and has a remarkable rigidity. It is very stable under extreme conditions, can be injected, and can be shaped according to the vessel it has been assembled in. The hydrogel allows a wide variety of possible biomedical applications including tissue engineering, axonal regeneration, and controlled drug release.