Tailoring Cell Adhesion Using Surface‐Grafted Polymer Gradient Assemblies | Zendy

Bhat R. R. | Zendy; Chaney B. N. | Zendy; Rowley J. | Zendy; LiebmannVinson A. | Zendy; Genzer J. | Zendy

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Tailoring Cell Adhesion Using Surface‐Grafted Polymer Gradient Assemblies

Author(s) -

Bhat R. R.,

Chaney B. N.,

Rowley J.,

LiebmannVinson A.,

Genzer J.

Publication year - 2005

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.200500858

Subject(s) - materials science , polymer , protein adsorption , grafting , adhesion , adsorption , chemical engineering , cell adhesion , surface modification , morphology (biology) , polymer chemistry , nanotechnology , biophysics , composite material , organic chemistry , chemistry , biology , engineering , genetics

Surface‐grafted polymer assemblies with a gradient in molecular weight (MW) and/or grafting density (σ) are used to tune protein adsorption, which consequently governs cell adhesion. Increasing the surface coverage of the polymer by increasing the MW and/or σ results in a decrease in the amount of protein adsorbed, which causes a decrease in the number of cells adhered and a change in cell morphology.

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