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A Reagentless Biosensing Assembly Based on Quantum Dot–Donor Förster Resonance Energy Transfer
Author(s) -
Medintz I. L.,
Clapp A. R.,
Melinger J. S.,
Deschamps J. R.,
Mattoussi H.
Publication year - 2005
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200500722
Subject(s) - cyanine , quantum dot , förster resonance energy transfer , photoluminescence , biosensor , energy transfer , materials science , resonance (particle physics) , acceptor , nanotechnology , fluorescence , chemistry , chemical physics , optoelectronics , physics , optics , atomic physics , condensed matter physics
On the surface of a quantum dot (QD) , maltose‐binding protein (MBP, white and yellow in Figure) labeled with a cyanine dye (red) self‐assembles, resulting in F?rster resonance energy transfer between the acceptor dye and the QD donor. Upon binding maltose, MBP undergoes a conformational change (white ⇌ yellow), causing concentration‐dependent photoluminescence changes.