Premium
Mesoporous Silica Particles as Templates for Preparing Enzyme‐Loaded Biocompatible Microcapsules
Author(s) -
Yu A.,
Wang Y.,
Barlow E.,
Caruso F.
Publication year - 2005
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200402045
Subject(s) - materials science , template , mesoporous silica , biocompatible material , mesoporous material , chemical engineering , adsorption , dispersion (optics) , nanoparticle , nanotechnology , spheres , salt (chemistry) , organic chemistry , catalysis , chemistry , biomedical engineering , medicine , physics , engineering , optics , astronomy
Following enzyme adsorption within the pores of mesoporous silica template spheres, polypeptide multilayers are assembled on the particles, and the template is dissolved. This yields a high concentration of enzyme in an active state within the microcapsules (microcapsules are shown in the Figure), which can be released upon changing the pH or salt concentration of the dispersion medium.