Ferrocene‐Functionalized Cationic Polythiophene for the Label‐Free Electrochemical Detection of DNA | Zendy

Le Floch F. | Zendy; Ho H.A. | Zendy; HardingLepage P. | Zendy; Bédard M. | Zendy; NeaguPlesu R. | Zendy; Leclerc M. | Zendy

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Ferrocene‐Functionalized Cationic Polythiophene for the Label‐Free Electrochemical Detection of DNA

Author(s) -

Le Floch F.,

Ho H.A.,

HardingLepage P.,

Bédard M.,

NeaguPlesu R.,

Leclerc M.

Publication year - 2005

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.200401474

Subject(s) - cationic polymerization , polythiophene , ferrocene , peptide nucleic acid , materials science , nucleic acid , dna , combinatorial chemistry , polymer , electrochemistry , conductive polymer , nanotechnology , polymer chemistry , electrode , chemistry , biochemistry , composite material

Specific, sensitive detection of unlabeled target DNA at room temperature is reported. A new, water‐soluble, ferrocene‐functionalized, cationic polythiophene is synthesized. This conducting polymer, used together with gold‐bound peptide nucleic acid (PNA) probes, makes, by a simple electrostatic method, DNA detection possible (see Figure).

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