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Freeze‐Drying of Soft Nanoparticles with Projection Coronas Forms Three‐Dimensional Microconstructs
Author(s) -
Kaneko T.,
Hamada K.,
Chen M. Q.,
Akashi M.
Publication year - 2005
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200401288
Subject(s) - nanoparticle , projection (relational algebra) , materials science , colloid , nanotechnology , microsphere , polymer science , chemical engineering , computer science , algorithm , engineering
Freeze‐drying of polymeric nanoparticles with projection coronas results in the successful formation of three‐dimensional microconstructs with various morphologies, including hollow microspheres (see Figure), without a solid or colloidal template. The microconstructs have sufficient mechanical strength to redisperse successfully in water without collapsing, while they break into nanoparticles following successive freeze–thawing cycles.