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Electroactive Substrates that Reveal Aldehyde Groups for Bio‐Immobilization
Author(s) -
Yeo W. S.,
Mrksich M.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200400591
Subject(s) - aldehyde , ligand (biochemistry) , substrate (aquarium) , materials science , combinatorial chemistry , labelling , self assembled monolayer , monolayer , nanotechnology , organic chemistry , chemistry , biochemistry , receptor , biology , catalysis , ecology
An electroactive substrate (see Figure) that reveals aldehyde groups in response to an oxidative potential is reported. The process is based on monolayers that can be switched to initiate the selective immobilization of an amino functionalized ligand, and marks a significant advance over previous dynamic substrates that have initiated the immobilization of a ligand, since it reveals a functional group that does not require labelling of a ligand.