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Bioactive Hydrogels with an Ordered Cellular Structure Combine Interconnected Macroporosity and Robust Mechanical Properties
Author(s) -
Stachowiak A. N.,
Bershteyn A.,
Tzatzalos E.,
Irvine D. J.
Publication year - 2005
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200400507
Subject(s) - materials science , self healing hydrogels , porosity , void (composites) , colloidal crystal , nanotechnology , composite material , colloid , chemical engineering , polymer chemistry , engineering
A method for preparing porous hydrogel scaffolds suitable for bioengineering applications based on colloidal‐crystal templating is demonstrated. Templated scaffolds are shown to have highly interconnected porosities at moderate void fractions due to their ordered arrangement of voids, and thus combine abundant pathways for cell migration (see Figure) and mass transport with compressive moduli comparable to soft tissues.