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Enzymatic Formation of Supramolecular Hydrogels
Author(s) -
Yang Z.,
Gu H.,
Fu D.,
Gao P.,
Lam J. K.,
Xu B.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200400340
The enzymatic formation of supramolecular hydrogels is reported. A dephosphorylation enzymatic reaction (see Figure) triggers the self‐assembly of N ‐(fluorenyl‐methoxycarbonyl) tyrosine and results in hydrogelation at physiological temperatures. This enzymatic gelation process offers opportunities for in‐situ generation of hydrogels in tissues and demonstrates potential for biomedical applications of supramolecular hydrogels.