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Biomimetic Coating of Laminin–Apatite Composite on Titanium Metal and Its Excellent Cell‐Adhesive Properties
Author(s) -
Uchida M.,
Oyane A.,
Kim H.M.,
Kokubo T.,
Ito A.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200400152
Subject(s) - materials science , titanium , adhesion , composite number , apatite , adhesive , coating , layer (electronics) , composite material , metal , titanium alloy , laminin , cell adhesion , cell , chemical engineering , metallurgy , engineering , genetics , alloy , biology
A laminin–apatite composite layer (see Figure) with superior cell‐adhesion properties that has been formed on the surface of titanium metal without denaturation of the laminin is reported. Application of the composite to titanium materials is expected to prevent bacterial infection, and it is therefore believed that this material could be useful for percutaneous implants, such as artificial tooth roots or skin terminals.