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Membrane Photolithography: Direct Micropatterning and Manipulation of Fluid Phospholipid Membranes in the Aqueous Phase Using Deep‐UV Light
Author(s) -
Yee C. K.,
Amweg M. L.,
Parikh A. N.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200306498
Subject(s) - micropatterning , photolithography , membrane , phospholipid , materials science , aqueous solution , nanotechnology , phase (matter) , lithography , aqueous two phase system , nanofluidics , lipid bilayer , chemical engineering , chemistry , optoelectronics , organic chemistry , biochemistry , engineering
A wet photolithography approach using light‐activated, localized, oxidative chemistry can directly pattern fluid phospholipid bilayers submerged in aqueous phases. Targeted incorporation of secondary components within pattern voids (see Figure) allows many membrane dynamical processes to be probed and optically defined arrays of holes, functional membrane microdomains, and proteins embedded in a lipidic background can be designed.