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Novel Citric Acid‐Based Biodegradable Elastomers for Tissue Engineering
Author(s) -
Yang J.,
Webb A. R.,
Ameer G. A.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200306264
Subject(s) - materials science , biodegradation , elastomer , biocompatibility , citric acid , tissue engineering , polymerization , monomer , biodegradable polymer , porosity , characterization (materials science) , chemical engineering , polymer , composite material , biomedical engineering , nanotechnology , organic chemistry , chemistry , metallurgy , medicine , engineering
The synthesis and characterization of novel biodegradable elastomers , exemplified by poly(1,8‐octanediol‐ co ‐citric acid), is reported. Biodegradation, mechanical, and biocompatibility data suggest very good potential for use as porous scaffolds in cardiovascular tissue engineering (see Figure). Material properties can be tailored by modulating the monomer ratio and post‐polymerization conditions.